Find Places to Stay in Florence County, South Carolina

In addition to noteworthy dining experiences, popular family-friendly attractions, fun-filled outdoor activities, and premier shopping spots, Florence County is home to an array of excellent lodging options—all conveniently located off I-95 and I-20.

For a uniquely Florence experience, consider staying at:

  • Ambrias Garden Manor, a top-rated B&B
  • Hotel Florence, a Hilton experience in a historic hotel
  • Olive’s Bed & Breakfast, a family-friendly farm stay
  • The Inn at the Crossroads, a one-of-a-kind hotel experience in a beautifully renovated historic property with an on-site restaurant.

If you prefer the comforts of your favorite hotel brands, you have more than 4,000 rooms to choose from.

To learn more about a specific location and to search for rates and availability, click on the “More Information,” button, where you’ll find the company’s or individual’s contact information and website. 

Affordable Suites of America

Ambrias Garden Manor

Baymont by Wyndham Florence

Best Western Inn

Comfort Inn & Suites

Comfort Suites

Country Inn & Suites

Courtyard Florence

Days Inn – Florence/I-95

Days Inn – Lake City

Econo Lodge

Fairfield Inn & Suites

Florence Inn & Suites

Hampton Inn & Suites Florence Center

Hampton Inn & Suites I-95

Hilton Garden Inn

Holiday Inn Express & Suites/Florence Center

Holiday Inn Express & Suites/Hwy 327

Home2 Suites

Homewood Suites

Hotel Florence

Howard Johnson

Hyatt Place

Knights Inn

La Quinta Inn & Suites

Microtel Inn & Suites

Olive’s Bed & Breakfast

Quality Inn & Suites – Florence Center

Quality Inn & Suites – Lake City

Red Roof Inn

Residence Inn

Springhill Suites

Staybridge Suites

Suburban Extended Stay

The Inn at the Crossroads

Towneplace Suites


Tru by Hilton